| Date | Location | Result | |
| Nov 18, 2000 | Unknown | FUR 3, Coll. of Charleston 1 (18-16,15-9,14-16,15-9) | Box score |
| Nov 17, 2000 | Charleston, SC | Coll. of Charleston 3, Chattanooga 0 (16-14,15-12,15-12) | Box score |
| Nov 14, 2000 | Charleston, SC | Charleston Southern 3, Coll. of Charleston 2 (15-10,9-15,5-15,15-13,15-8) | Box score |
| Nov 12, 2000 | Charleston, SC | Western Carolina 3, Coll. of Charleston 1 (10-15,15-11,15-8,15-9) | Box score |
| Nov 11, 2000 | Charleston, SC | Chattanooga 3, Coll. of Charleston 0 (15-12,15-0,15-12) | Box score |
| Nov 07, 2000 | Charleston, SC | Coll. of Charleston 3, The Citadel 0 (15-5,15-2,15-12) | Box score |
| Nov 04, 2000 | Johnson City, TN | East Tennessee State 3, Coll. of Charleston 0 (16-14,15-12,15-13) | Box score |
| Nov 03, 2000 | Boone, NC | Appalachian State 3, Coll. of Charleston 1 (15-13,15-9,13-15,15-13) | Box score |
| Oct 28, 2000 | Greensboro, NC | Coll. of Charleston 3, UNC Greensboro 1 (15-11,15-4,14-16,15-9) | Box score |
| Oct 27, 2000 | Davidson, N.C. | Davidson 3, Coll. of Charleston 2 (13-15,15-10,8-15,15-1,15-12) | Box score |
| Oct 22, 2000 | Charleston, SC | Coll. of Charleston 3, Wofford 1 (15-10,15-13,13-15,15-12) | Box score |
| Oct 21, 2000 | Charleston, SC | Furman 3, Coll. of Charleston 1 (15-8,3-15,15-11,15-9) | Box score |
| Oct 17, 2000 | Conway, SC | Coastal Carolina 3, Coll. of Charleston 1 (12-15,15-10,15-10,15-6) | Box score |
| Oct 12, 2000 | Statesboro, GA | Coll. of Charleston 3, Georgia Southern 1 (10-15,15-3,15-10,15-5) | Box score |
| Oct 10, 2000 | Charleston, SC | Coll. of Charleston 3, The Citadel 0 (17-15,15-10,15-6) | Box score |
| Oct 07, 2000 | Cullowhee, NC | Western Carolina 3, Coll. of Charleston 2 (15-5,9-15,15-6,10-15,16-14) | Box score |
| Oct 06, 2000 | Chattanooga, TN | Chattanooga 3, Coll. of Charleston 2 (5-15,15-7,12-15,15-10,15-9) | Box score |
| Sep 30, 2000 | Charleston, SC | East Tennessee State 3, Coll. of Charleston 0 (15-11,15-12,15-6) | Box score |
| Sep 29, 2000 | Charleston, SC | Coll. of Charleston 3, Appalachian State 0 (15-10,15-12,15-10) | Box score |
| Sep 26, 2000 | Charleston, SC | Coll. of Charleston 3, Charleston Southern 0 (15-11,16-14,15-8) | Box score |
| Sep 23, 2000 | Charleston, SC | Davidson 3, Coll. of Charleston 1 (16-14,15-17,16-14,15-11) | Box score |
| Sep 22, 2000 | Charleston, SC | Coll. of Charleston 3, UNC Greensboro 0 (15-10,15-11,15-8) | Box score |
| Sep 18, 2000 | Greenville, SC | Furman 3, Coll. of Charleston 0 (15-8,15-10,15-6) | Box score |
| Sep 17, 2000 | Wofford College | Coll. of Charleston 3, Wofford 0 (15-9,15-5,15-7) | Box score |
| Sep 12, 2000 | Charleston, SC | Coll. of Charleston 3, Coastal Carolina 1 (15-10,17-19,15-6,15-9) | Box score |
| Sep 09, 2000 | Charleston, SC | Memphis 3, Coll. of Charleston 0 (17-15,15-10,15-8) | Box score |
| Sep 08, 2000 | Charleston, SC | Coll. of Charleston 3, Mercer 1 (15-2,15-12,11-15,15-0) | Box score |
| Sep 08, 2000 | Charleston, SC | Coll. of Charleston 3, SC State 0 (15-7,15-8,15-5) | Box score |
| Sep 05, 2000 | Charleston,SC | Georgia Southern 3, Coll. of Charleston 1 (15-13,15-13,11-15,17-15) | Box score |
| Sep 02, 2000 | Austin Peay State | Coll. of Charleston 3, Christian Brothers 0 (15-7,15-4,15-3) | Box score |
| Sep 01, 2000 | Austin Peay State | Austin Peay State 3, Coll. of Charleston 0 (15-5,15-9,15-12) | Box score |
| Sep 01, 2000 | Clarksville, TN | Coll. of Charleston 3, Belmont 0 (16-14,15-9,15-9) | Box score |